居住在洛杉矶的除虫专家亚历克斯·马迪斯（格雷戈·格伦伯格 Greg Grunberg 饰）在一次工作中被褐皮蜘蛛咬伤，他到医院就诊，结果殓房一名医护人员被某具尸体里爬出的巨型蜘蛛攻击，留下难以置信的可怕伤口，正为医药费发愁的亚历克斯自告奋勇前去解决。与此同时，美国军方一对人马全副武装来到医院，宣布对此实施封锁。原来那只神秘蜘蛛来自军…

该季将集中塑造瓦坎，讲述黑豹兄妹与自己的老敌人“影子内阁”斗争的故事。

故事的主人公是一个年轻的女演员。某天她无意间吃了舍友的一炉里面含有大麻的蛋糕，结果其后的一天内遭遇了很多让人发狂的事情……

The Avengers gather to celebrate their latest victory, but their celebration is quickly interrupted by the mysterious disappearance of Black Widow’s father, Red Guardian. As the Avengers investigate, they discover that Red Guardian isn’t t…

While looking for a way back to Earth, the Hulks discover the Leader stowed away on board the ship. Retribution must wait as the Agents of S.M.A.S.H. have to fight Ronan the Accuser and his Kree soldiers to save an old foe: Ego the Living Planet. But when Galactus comes to consume Ego the Living Planet, the Agents of S…